The armamentarium of neuroimaging is becoming increasingly versatile. Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in determining the etiology of focal epilepsy and demonstrating the anatomical changes associated with seizure activity. Epilepsy is a common neurological disorder with diverse etiologies. Lorenzo used MRI to identify abnormal patterns of activity in an area of the brain known as the thalamus, laying the foundations for future work aimed at developing therapeutic approaches to prevent these seizures in TLE. Lorenzo’s research has given important new insights to three common epilepsy syndromes. doi: 10.1371/journal.pone.0219904. Please enable it to take advantage of the complete set of features!  |  Clipboard, Search History, and several other advanced features are temporarily unavailable. Epilepsy is the most common neurological disease worldwide and is second only to stroke in causing neurological morbidity. Epub 2020 Feb 6. Lorenzo’s third project investigated brain structure and function in patients with Juvenile Myoclonic Epilepsy (JME) and their unaffected siblings. Try Â. Find out about our other research in this area: We need you to know about our Website Terms and our Privacy Policy. Computational analysis in epilepsy neuroimaging: A survey of features and methods.  |  Everyday low prices and free delivery on eligible orders. She is now a qualified nurse and has a two-year-old son, Archie. 2020 Jun;41(6):987-993. doi: 10.3174/ajnr.A6545. Close this message to accept … 7345516. These have different symptoms and features but have in common that they cause repeated seizures - like electrical storms that briefly interrupt the brain's normal activity. The aim was to identify heritable traits associated with the disease. eCollection 2020. 2020 Mar;63(3):88-95. doi: 10.3345/kjp.2019.00871. doi: 10.12688/f1000research.17714.1. Neuroimaging in Epilepsy - Oxford Scholarship. He wanted to understand whether there is progression of brain abnormalities associated with the disease i.e. Epilepsy neuroimaging is important for detecting the seizure onset zone, predicting and preventing deficits from surgery and illuminating mechanisms of epileptogenesis. We use cookies and similar tools to enhance your shopping experience, to provide our services, understand how customers use our services so we can make improvements, and display ads. Neuroimaging in Epilepsy: Towards Structural Cellular Imaging - Volume 39 Issue S6 - Ruben Kuzniecky. A company limited by guarantee. In most patients seizures can be controlled with medication, but there are other cognitive, personal and psychiatric disturbances ('comorbidities') that detrimentally impact the lives of those affected. NIH This PhD studentship enabled Lorenzo to work for four years in the world-renowned National Hospital for Neurology and Neurosurgery in Queen Square, London, home to cutting-edge clinical and translational research. FDG-PET Profiles of Extratemporal Metabolism as a Predictor of Surgical Failure in Temporal Lobe Epilepsy. Altered temporal dynamics of brain activity in patients with generalized tonic-clonic seizures. In the long-term, he aspires to specialise as a neurologist, focusing his clinical and research work on advancing the understanding of epilepsy and, specifically, the translation of knowledge to the clinic to inform prognostic assessments,rehabilitation approaches, and the development of treatment strategies to improve patient care. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. These have different symptoms and features but have in common that they cause repeated seizures - like electrical storms that briefly interrupt the brain's normal activity. The second part of this project focused on convulsive seizures in TLE. Neuroimaging CT scans. A Study on Hippocampal Atrophy in Mesial Temporal Lobe Epilepsy. (1)Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. Advanced features are temporarily unavailable and genetic biomarkers to enable personalized epilepsy.... Faculty Rev-1818 EEG, and neuroimaging, is necessary to localize the likely epileptogenic region provides powerful. 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